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Jillian Simon founded The Endoura Effect with one purpose: to help people feel like themselves again—energized, balanced, and in sync with their biology. A board-certified Family Nurse Practitioner with advanced expertise in hormone optimization, thyroid health, peptide therapy, and metabolic medicine, Jillian blends the science of longevity with the art of personalization. Her philosophy is grounded in curiosity and collaboration. When you understand the unique code that makes you you, healing stops being guesswork—it becomes design.
Every experience at The Endoura Effect is intentionally crafted to create alignment—from hormones to metabolism to mindset. Care here goes beyond prescriptions and protocols; it’s about decoding biology, restoring rhythm, and helping people move through life with clarity and intention again.
As the Founder and Clinical Director of The Endoura Effect, Jillian Simon is leading a new era of precision wellness—where data, genetics, and human connection converge.
Her clinical work spans hormone replacement therapy (HRT/TRT), thyroid optimization, GLP-1 metabolic therapies, and advanced peptide and longevity protocols. Drawing from her background in epigenetics and functional medicine, Jillian integrates DNA-driven insights into every patient plan—tailoring care at the cellular level to unlock each person’s potential for vitality and resilience.
Before founding The Endoura Effect, Jillian built and scaled a multi-state telehealth practice that became a prototype for the future of personalized medicine. That innovation later evolved into her next venture: developing data-informed tools and clinical systems that power precision care models for clinics nationwide.
Beyond the clinic, Jillian serves as president of a nonprofit mentoring young women in leadership and confidence—a reflection of her belief that empowerment in health begins with empowerment in self. She’s also a wife and mother, navigating the same real-life rhythms she helps her patients restore—proof that wellness isn’t about perfection, but presence.
Her vision is clear: to elevate healthcare into a space that’s personal, intelligent, and profoundly human—where medicine isn’t just reactive, but restorative.
Jillian believes precision medicine isn’t just about data—it’s about translating that data into meaning, and that meaning into healing. The Endoura Effect exists to make that translation possible.
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